Epidemly and biostats Assignment Example | Topics and Well Written Essays - 750 words

Epidemly and biostats - Assignment Example To do this, they have to contact hospitals and physicians. This activity requires a vast amount of resources and staff in order to accomplish its objectives and goals. a) The conclusion reached may be incorrect because proportional mortality was used when cause-specific mortality rates were needed. Cause specific rates are applied when calculating deaths from a specific disease (Polit, 2010). Proportionate mortality is applied when calculating the number of deaths in relation to the total deaths or all deaths (100%) a) The number of deaths from lung cancer in carpenters in 1949–1960 was greater than the number of deaths from lung cancer in bricklayers during the same period. SMR is often used to study the mortality in a specific occupation. From the data, carpenters have a higher mortality than brick layers during the same period. a)Reduce selection bias in the allocation of treatment. Treatment differences which are identified from nonrandomized trial designs possess methodological weaknesses. For example, cohort effects, selection bias and confounding. As such, the major purpose of a random assignment is to counter this methodological weakness. a)Avoid observer and subject bias. A double blind experiment design tests a drug or treatment’s effect by using groups of control and experimental subjects whereby neither the investigators nor the subjects know which drug is being used on which group (Grove, 2007). Therefore, this design eliminates the issue of prejudgment which can distort the

Barriers to Meaningful Instruction for English Learners Research Proposal

Barriers to Meaningful Instruction for English Learners - Research Proposal Example On the other hand, there are non-verbal languages, which entail the way a person, stands or carries themselves, and behaviors such as holding of their hands and arms during a conversation and facial expressions, and these cues have a significant effect on the communication. For instance, there are difficulties involved in a conversation where someone has their arms closed across their chest since this signifies a defensive pose. Therefore, in order to solve problems associated with cultural and non-verbal barriers, there is a need to use several mediums of communicating with people. Furthermore, I have identified them to focus on the medium used in communication while communicating with people since each situation suits a certain medium such as face-to-face, over the phone, through text messaging or emails. Therefore, I have learned the role of determining the medium, which suits a certain message in a given situation, for instance, a one should not avoid face-to-face communication b y using text messages or emails; instead, they should focus on selecting the medium that suits every situation. Critical thinking Skills I am seeking to improve my critical thinking skills, which are applied  constantly  in my life and they have  various  benefits and  significance. It is  indispensable  for everyone to learn about critical thinking skills and their  applications in order to make better decisions. Critical thinking involves  mental  processes of analysis, discernment, and evaluation. It entails the possible processes for the reflection upon the tangible and intangible to  form  a judgment that is  informed  and  solid  to reconcile the  scientific  evidence involving common sense (Ennis, 1978, 321). I understand that as a critical thinker, I will have the ability to gather relevant information from  various  senses, both verbal and written expressions, experiences, reflection, reasoning, and observation. According to Elder (20 08, 43), the process of critical thinking involves thinking about a  certain  problem or  subject  in order to get to a point of the improvement in the quality of thinking through skillful analogies. Therefore, the application of critical thinking in various aspects of life has  numerous  benefits in the process of decision making Language Skills English is like an international language spoken worldwide, and it is accepted  in a way that everyone  is expected  to learn to speak English as a tool to be applied in bridging "in international divides and borders". There are various reasons for everyone to consider having English as a second language. There are those who  learn  a new language in  various  ways, the most profound  way  of learning is through the internet.

How can understaning elasticity of demand help a firm in its Essay

How can understaning elasticity of demand help a firm in its planningExplain how the different levels of elasticity influence behaviour within different market structures - Essay Example Elasticity of demand explains the extent to which consumers are willing to relinquish their consumption of a particular product due to price increase and vice versa. Upon setting goals and objectives of the firm, the management ought to strategise and plan operations that facilitate goal achievement. As noted earlier, revenues can be raised by either raising quantity supplied via expansion or altering prices. Quantity supply increment is associated with increase in costs and thus requires careful analysis and hence a long-term decision. On the other hand, due to the negative effect that price has on sales; its increment does not necessarily result to increased revenue, but rather depends on the proportionate change in quantity demanded. For that reason, decision maker ought to consider elasticity of demand before initiating a price alteration. As matter of fact, increase in price may either raise or lower total revenue, though it has no effect on cost. Moreover, planners ought to understand the determinants of elasticity and work, to their advantage, either to increase or reduce it. In an inelastic demand situation, a change in price results to a less than proportionate change in sales. A rational firm may therefore increase price as it adds to revenues. However, as price the consumer surplus reduces and hence consumer’s responsiveness to price increases (Guru, 2010). At the point where elasticity becomes unitary, it makes no economical sense to raise price, since the impact on revenues is negligible if not zero. Alternatively, reducing prices on elastic commodities increases revenues and vice versa. Remarkably, in an elastic situation, the change in price is offset b the more than proportionate change in quantity demanded. Among many other factors, elasticity ought to be a key variable in pricing policies. Secondly, elasticity of demand can be used to predict availability and

Free Market Economy and Financial Crisis Essay Example | Topics and Well Written Essays - 1250 words

Free Market Economy and Financial Crisis - Essay Example The companies had come to this point of crisis because free market had allowed them to make investments due to which the institutions were posed to risks. Millions of people in America lost their jobs and had their savings bushed. A number of factors have been blamed for this crisis but economists believe that free market is the very basic factor amongst all. Nobel laureate Joseph Stiglitz wrote in his book Freefall that market fundamentalists and deregulators are responsible for the mess. The situation showed that free-market economists failed and market fundamentalists were responsible for the economic crunch (Sorman 2010). The economy of United States of America witnessed only a few minor recessions each for a short period of time. Those recessions did not stir the economy enough to cause economists to develop a well descriptive recession model. With no major recessions over a long time, the economists tend to believe that the crisis may not happen. The model derived by free marke t economists was running a healthy economy from 80s to 2008 making economists believe that the model may not turn the situation upside down (Sorman 2010). The free market economists argue that it is the recession that prompted the financial crisis and not the other way around. Economists believe that recession began in 2007 when consumer spending decreased, overdue borrowing increased and lack of interest of homeowners in their mortgaged houses increased. They claim that the failure of financial derivatives were not the cause of financial turmoil as they were helping in the stabilization of the economy. Economists assume that due to a sudden economic downfall government faced pressure from political and non political forces to take immediate steps. This led to government spending and its intervention in the scenario which seemed quite logical at that time. The situation worsened with new public debts and regulations which stumbled upon the recovery of the economy (Sorman 2010; Bordo et al 2010). The economy could be recoiled in a quicker way if government had allowed enterprises to survive on their own by dealing with the crisis with an astute strategic approach. It is also believed that the financial turmoil was brought about by the recession but the initial slump was the result of energy cost as well. The US expenditure of energy as expressed in percentage of total spending had droppedfrom 8 to 5 percent between 1979 and 2004. The price of gasoline had hit $4 per gallon by June 2008, representing a sharp shift in energy share of total spending back to 7 per cent. The shift was due to the increased demand from evolving economies like China and India which soared up the prices. The price grabbed attention as the spending pattern showing a considerable upward movement was an indication of disruption. The unit sales of light truck curtailed by 23 per cent in the second quarter of 2008 in comparison to the preceding year’s 2nd quarter.The auto manufacturin g industry cut over 125,000 jobs during the same period. The energy prices affected transportation and hence the housing sector as the houses in the suburban region lost their value and attraction. Failure of the mortgage market came up as another blow in 2007, prior to the financial cri

My Vocational Profile Essay Example | Topics and Well Written Essays - 500 words

My Vocational Profile - Essay Example No one else can set the principles of one's ethics other than oneself. I give respect to people irrespective of their social standings and demand the same from others; though not in a reciprocative manner. Another thing is that I value work no matter however small and whatever kind it might be. Presently I am working part time as a waiter in a restaurant because it helps in getting some income and gives me a new opportunity to meet new people all the time. The activities of my interests might sound to be somewhat common but this is what they are. I like to visit new places and meet new people; especially people who are unlike me in thinking, in behaviour and in lifestyle. I try understand why they are what they are. I like to travel to different places, possibly alone, which gives me enough time to think and digest what I see. I like to learn new things from different sources. Reading also interests me a lot. The kind of readings includes current affairs, business trends, readings about various personalities and science related readings regarding latest discoveries and inventions. My dreams are the biggest source of my motivations. I am ambitious by nature.

Gates of Fire Essay Example for Free

Gates of Fire Essay Why I chose this book: I have no particular reason why I chose this book. While searching through the commandant’s new reading list, the title of the book stood out to me. It did not seam like a boring documentary or and endless biography that goes on and on but rather an interesting read that would keep me interested. When I went to go check it out from training I read the summary on the back of the book and was immediately intrigued about the storyline. I like the adventure and thrill of the Spartans as well as reading about war battles. Give a brief description about this book: This book is about a legendary Battle of Thermopylae and the Spartan culture. In 480 BC the Persian Empire marched with a force of two million men against Greece. In Greeces defense a small army of 2,500 Greek soldiers marched out in an attempt to slow the Persian advance. 300 Spartans were among this squadron, willing to fight to the death for their homeland. The two armies crashed at the narrow pass of Thermopylae. For six days the small force held off the entire Persian army, inflicting an estimated 20,000 casualties on the enemy. On the seventh day the main Greek force withdrew. The remaining Spartan force and a small number of Thespians stayed giving their comrades time for escape. The residual Greek forces fought heroically to the death. The slowed Persian advance gave Greek forces added time to muster men and eventually repel the invasion. The author depicts the story from a Spartan soldiers squire (armor bearer) point of view. The armor bearer, Xeo, tells his life story from his youth as an outcast to his acceptation into the Spartan military. Through the eyes of Xeo, the author tells of an armor bearers duties, soldiers thoughts and attitudes, Spartas military training, and Spartas military based culture. While he tells that Sparta is a cruel and brutal military society he also tells of the beauty and love that the civilization also possesses. Tactical lessons learned from this book: Some of the tactical leassons I learned from this book come from the battle at Thermopylae. Some of the tactics that interestead me, even back in those days, is when the Spartan army first arived at Themopylae. They scouted the area to see it they could possibly be flanked by the opposing army. They rounded up all of the random people that were not part of the battle so that their opposition could not use them for land navigation. The Spartans even burnned all the fields of crops so that their foe could not use the crops for rations. It is clear to me that fighting a battle is not all about who is the better fighter. I learned that witts and logistics are key elements for victory. Leadership lessons learned from this book: One of the leadership lessons that could be learned from this book involves courage. On multiple occasions in the book the leadership tries to instill in their men the philosophy that training for war has little to do with strengthening the war fighter physically but rather to toughen the mind. Polynikes also had the men realize that any army can win a battle with its legs still under it, it is when all strength has fled and the men must produce victory on will alone. I learned that if I want my Marines to be the best, I have to expect the best as well as adopt this mentality so that I may lead by example. How can the lessons learned be used today: The spartans trained to achieve victory while face whith constant adversity. Today the younger generation has adopted the attitude of, if it can’t be done with a reassonable amount of effort, then it can’t be done and they give up. We as leaders can learn from the spartans will to push through anything against all odds. So, by pushing our Marines until they give up and then pushing them more with expectaions of exelence can be a useful tool in teaching our Marines that they can jump over the wall instead of running into it. I would or would not recommend this book to my peers, and why: The author gives interesting facts about Spartan culture, its soldiers, attitudes of religion, and gripping battle scenes. The novel is extremely entertaining and gives a fascinating insight into courage, discipline, love, and war. Based on all of these reason I would recommend this book to anyone who enjoys reading of history or war.

Amitraz Poisoning Management | Case Study

Amitraz Poisoning Management | Case Study Title of the article: Amitraz Poisoning – A rare pesticide Poisoning Abstract: Amitraz, an insecticide/acaricide of the formamidine pesticide group, is a alpha 2 adrenergic agonist used to a great extent in veterinary and agricultural products for the treatment of ectoparasitic manifestations. In the current article we report the findings of a case of 22 year old female who consumed about 50 ml Amitraz poison by oral route as a suicidal attempt. On arrival to Emergency Department the patient presented in deep comatose state, respiratory depression, bradycardia, hypotension, miosis, hypothermia, and hyperglycemia.she recovered completely within 48 hours with adequate supportive care. The case report throws considerable light on the management of Amitraz poisoning, good prognosis with early recognition, initial stabilisation, reducing absorption, supportive management with Iv fluids, airway management, monitoring urine output and other supportive care, very few cases of intoxications in human beings due to the pesticide have been published in literature It has be come imparative to intruct the pesticide manufacturers to initiate suitable measures to decrease the incidence of Amitraz poisoning by prominent and clear warning labels on the containers and potential hazards of the compound. Key-words: Amitraz; poisoning ; alpha 2 adrenergic agonist; miosis Key Messages [D1]: Introduction Amitraz, a triazapentadiene compound and a member of the amidine chemical family is a formamidine pesticides which is increasingly being used as an insecticide and an acaricide to control animal ectoparasites [1-3]. The formulations available for chemical use contain 12.5-50% in an organic solvent called xylene, which itself is used in plant cleaners and glues[4].Amitraz is a Alpha 2 adrenergic agonist stimulating alpha 2 adrenergic receptors in the Central Nervous System(CNS).and both alpha 1 and alpha 2 adrenergic receptors in the periphery. Poisoning occurs throgh oral, inhalational (the mostpotential), and dermal routes and is accompanied by numerous signs and symptoms varying from CNS depression (drowsiness, coma, and convulsion), to miosis, or rarely, mydriasis, respiratory depression, bradycardia, hypotension, hypothermia or fever, hyperglycemia, polyuria, vomiting, decreased gastrointestinal motility, and intestinal distension [4].Adverse effects and side effects have been re ported in animals exposed to the product : however only few cases of human toxication have been published in Indian literature. we present a young female patient with Amitraz poisoning who was conservatively managed with complete recovery hence significantly contributing to the limited human toxicological data. Case History[D2]: An 22 year old female was brought to our Emergency Department (ED) with a history of suicidal consumption of about 50 ml Amitraz poison eight hours before being brought to our ED, her first symptom had begun about 30 minutes post ingesion and included nausea and vomiting, thus she was taken to a hospital in their locality where intravenous crystalloids were started and referred to our centre. On arrival to our department the patient was deeply comatose with a GCS scale of 4/15. Her pulse rate, respiratory rate, blood pressure and temperature were 50/min, blood pressure was 92/64 mm of Hg, 16/minand 36.8 degree celsius respectively. On examination of CNS her pupil were bilaterally constricted, all four limbs had hypotonia and there was bilateral flexor plantar response. Other systemic examination were normal, there was no exessive oral secretions or any fasciculations.Gastric lavage with activated charcoal was given and patients airway was secured with endotracheal intubation due to l ow GCS.she was then admitted to ICU for further management her lab tests (Complete blood count, serum electrolytes, renal function tests, liver function tests), serum pseudocholinestrase levels, electrocardiography, routine urine tests and chest xray were normal except glucose level of 192 mg/dl.A urine test for drugs of abuse was negative and blood alcohol levels were normal. Ct brain plain was done which was normal.She was treated with supportive care in the ICU with IV Flluids, respiratory and cardiac monitoring, Atropine (once 2mg stat) was adminitered for transient bradycardia.over the next 24 hours she gradually improved and was extubated. Her vitals signs were Heart rate of 70/min and blood pressure was 110/70 mm of Hg. By the following day she was completely concious and was able to answer the question and she was shifted to general ward and was discharged after consultation with a psychiatrist. Discussion: Amitraz is increasingly being used worldwide in veterinary and agricultural products for the treatment of ectoparasitic manifestations. Formamidines show reversible toxic effects on both animals and humans [1]. The present knowledge about Amitraz and Foramine pesticides is usually built on animal studies as the available human intoxication is limited. It can cause poisoning in animals and humans via oral, inhalational or dermal routes. The toxicity from this poisoning can be attributed both Amitraz and the solvent, xylene. Although the ingested dose of Amitraz can not be determined because it is diluted 1 part in 500 before usage. The acute oral medical lethal dose(LD50) for the rats is 800/kg body weight.[3, 4]. The clinical features of this poisoning reported in previous reports include CNS depression, drowsiness, vomiting, miosis, bradycardia, hypotension, and hyperglycemia. The duration of CNS depression has ranged from a few hours to 24 h [4]. CNS symptoms began within 120-180 m inutes and resolved within 12-24 hrs in our case. Sedative effects of ÃŽ ±2-agonists are dose dependent[1]. Coma, absence of light reflex, and respiratory failure are due to the ingestion of greater amounts of amitraz supporting its dose-dependent effects. Our patient was fully conscious after 48hrs. This time has been reported to be 2-48 h in previous reports. The effect of amitraz on ÃŽ ±1– and ÃŽ ±2-receptors causes bradycardia [5]. In addition, literature reported hyperglycemia, hypotension, and bradycardia in amitraz poisoning and attributed them to the alpha-2 adrenoceptor agonist action of amitraz [6]. In our case, bradycardia was also present accompanying with miosis. Co-existence of bradycardia, miosis, and the respiratory depression leads to confusion with organophosphate or opioid poisonings, both of which should be excluded. Using atropine for treatment of bradycardia is controversial. Most studies, however, have reported atropine to resolve both miosis and bradycardia. Atropine is the first line therapy for the bradycardia resulted from vagal stimulation and atrioventricular blocks. Alpha-2 adrenergic drugs can also cause bradycardia by stimulating the dorsal motor nucleus of the vagus nerve. Studies have shown that atropine increases the heart rate and prevents Amitraz induced bradycardia in Animals(2). In our patient atropine was given once with the adult dose. Amitraz and its active metabolites inhibits insulin and stimulate glucagon secretion, hyperglycemia was detected in our case as reported in previous studies by Demirel and colleagues[7] Kalyoncu and colleagues have reported hyponatremia in their three cases[9], Usually BUN, creatinine, serum sodium and potassium do not change with this poisoning, in our case creatinine, serum potassium and sodium were normal. Kalyoncu and associates have reported respiratory alkalosis in two, respiratory acidosis in three and metabolic acidosis in five cases[9], in our patient the analysis of blood gases were normal. Avsarogullari et al reported hyperglycemia and fast deterioration of the patients with amitraz poisoning(within 5 minutes of ingestion of toxin)[8] Whenever a patient presents with bradycardia and miosis, organophosphorus compound poisoning should be considered as a differential diagnosis a along with Amitraz. Other signs and symptoms of organophosphorus compound should be looked for and a cholinesterase level should be done. Amitraz levels in blood was not done because it was unavailable at our institute and other referral laboratories. It is made clear that the basic approach to a patient with amitraz poisoning involves initial stabilisation, reducing absorption and increasing elimination of the toxin. there is no specific antidote[2] medical management involves supportive measures like gastric lavage, activated charcoal administration and securing the airway. Depending on the patients condition additional measures like oxygen supplementation or mechanical ventilation for respiratory depression, atropine for severe bradycardia, intravenous fluids and vasopressors for hypotension, diazepam or lorazepam for seizures. This case report throws considerable light on the management of Amitraz poisoning, good prognosis with early recognition and timely supportive management as the available human toxicological data are limited. When appropriate timely supportive treatment is given, Amitraz intoxication in humans caries a low morbidity and mortality inspite of rapidly progressing and life threatening clinical picture. It has become imperative to instruct the pesticide manufacturers to initiate suitable measures to decrease the incidence of Amitraz poisoning  by placing prominent and clear warning labels on containers. References[D3]: Queiroz-Neto A, Zamur GSC, Carregar O AB, 182 Motoqueiro MI, Harkins JD, Tobin T. Characterization of the 183 antinociceptive and sedative effect of amitraz in horses. J Vet 184 Pharmacol Ther 1998; 21:400-5. 1852. Agin H, Calkavur S, Uzun H, Bak M. Amitraz poisoning: clinical and laboratory findings. Indian Pediatr 2004; 41:482-6. Eizadi-Mood N, Sabzghabaee AM, Gheshlaghi F, Yaraghi A. Amitraz Poisoning Treatment: Still Supportive? Iran J Pharmaceut Res 2011; 10:155-8. Shitole DG, Kulkarni RS, Sathe SS, Rahate PR. Amitraz poisoning-an unusual pesticide poisoning. J Assoc Physicians India 2010; 58:317-9. Jorens PG, Zandijk E, Belmans L, Schepens PJ, Bossaert LL. An unusual poisoning with the unusual pesticide amitraz. Hum Exp Toxicol 1997; 16:600-1. Jones RD. Xylene/amitraz: a pharmacologic review and profile. Vet Hum Toxicol 1990; 32:446-8. Demirel Y, Yilmaz A, Gursoy S, Kaygusuz K, Mimaroglu C. Acute amitraz intoxication: retrospective analysis of 45 cases. Hum Exp Toxicol 2006; 25:613-7. Avsarogullari L, Ikizceli I, Sungur M, Sà ¶zà ¼er E, Akdur O, Yà ¼cei M. Acute amitraz poisoning in adults: clinical features, laboratory findings, and management. Clin Toxicol (Phila) 2006; 44:19-23. Kalyoncu M, Dilber E, Okten A. Amitraz intoxication in children in the rural Black Sea region: analysis of forty-three patients. Hum Exp Toxicol 2002; 21:269-72. [D1]1 Provide appropriate messages of about 35-50 words to be printed in centre box [D2]1 Include the tables/charts at appropriate places in the text it self. Do not include images in the text. Mark the point of insertion of images (e.g. Figure 1) along with the legends. Send the images separately as jpeg files (not larger than 100 kb each) [D3]1 Follow the punctuation marks carefully. Do not include unnecessary bibliographic elements such as issue number, month of publication, etc. Include names of six authors followed by et al if there are more than six authors.